Thursday 15 November 2018
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Gene discovery could increase understanding of Alzheimer's disease

Scientists have discovered a gene with a link to Alzheimer’s disease according to a new study published in the journal PLoS Genetics.

The genome-wide association study looked at the role of different genes in more than 2,000 people without Alzheimer's and more than 3,000 with the disease. They found the gene, MTHFD1L, also influences the amount of the protein homocysteine in the blood. High levels of this protein are a known risk factor for Alzheimer's disease.
Alzheimer's Society comment:

'In order to move closer to a cure and treatments for Alzheimer's it is essential for scientists to gain a better understanding of the causes of the disease. This interesting early research provides a new avenue of investigation but we still have a lot more to learn about this gene before we can determine its exact role.'

'One in three people over 65 will die with dementia and there will be over a million people living with the condition in less than 15 years. However dementia research is desperately underfunded. We need greater investment if we are to tackle dementia head on.'

Dr Susanne Sorensen
Head of Research
Alzheimer's Society